Mar 1, 2008
By:
Kenneth L. Busch
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Columnist Ken Busch presents the third of a five-part series on quantitative mass spectrometry. In this installment, he focuses on an overview of regression analysis for calibration lines and curves in mass spectrometry.
Jan 1, 2008
By:
Kenneth L. Busch
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In this month's installment, columnist Ken Busch addresses the molecular applications of inductively coupled plasma linked with mass spectrometry (ICP-MS), and how those applications have developed.
Oct 1, 2007
By:
Kenneth L. Busch
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In this month's installment, columnist Ken Busch continues his discussion of quantitative mass spectrometry with a look at the "cancel out" claim and some of the statistical underpinnings for the proportional comparison of instrument responses for standard knowns and unknowns.
Jul 1, 2007
By:
Kenneth L. Busch
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In this month's installment, columnist Ken Busch discusses how to best answer the questions "What is it?" and "How much is there?"
Apr 1, 2007
By:
Kenneth L. Busch
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In this month's installment, columnist Ken Busch presents an elementary explanation of mass spectrometry that is appropriate for a young student audience, or for, perhaps just explaining to family what you actually do for a living.
Jan 1, 2007
By:
Kenneth L. Busch
|
January 2007. In recent columns, the careful work needed to characterize and optimize electron ionization (EI) sources was described. This month, Ken Busch focuses on the potential for mass discrimination in the ICP source.
Oct 1, 2006
By:
Kenneth L. Busch
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October 2006. Columnist Ken Busch continues his discussion of the El source and how source design and operational details directly affect source performance.
Jul 1, 2006
By:
Kenneth L. Busch
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The ion source is the heart of the mass spectrometer. In the ion source, ions are created from gas-phase neutral sample molecules, or preformed ions are extracted from solutions, and then sent into the mass analyzer of the instrument. The electron ionization (EI) source was the first source widely used for organic mass spectrometry (MS), and design, development, and optimization of this source are all the result of the work of many of the early pioneers of MS.
Apr 1, 2006
By:
Kenneth L. Busch
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In addition to expressing his longing for a Star Trek "tricoder," columnist Ken Busch shows that the core processes of ionization, ion dissociation, and mass determination in mass spectrometry are all completed in very short times compared to the overall length of the analysis.
